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Bush: Smallpox Vaccine Is Your Call 

White House plan suggests voluntary inoculations for most of nation 

< December 12, 2002 > The Bush administration is leaving it up to you to decide if you want to receive the controversial smallpox vaccine.

But by making immunization voluntary, the White House has left Americans in the difficult position of having to weigh the theoretical risks of a smallpox attack with the small but concrete odds of suffering a serious or deadly side effect from the vaccine.

Under the Bush plan, expected tomorrow, as many as a half million soldiers will be required to receive the vaccine. They will be followed by up to about 10 million health and emergency personnel, the so-called "first responders" charged with immunizing others and containing infections in the event of an attack with the frequently deadly virus.

The rest of the nation will have the option of getting vaccinated, possibly beginning in 2004. The smallpox vaccine is effective against the virus, but it can lead to deadly complications in about one in every one million people who receive it. Another 10 to 15 per million suffer serious side effects, such as severe rashes.

"I think it ought to be a voluntary plan. I don't think people ought to be compelled to make the decision which they think is best for their family," Bush told ABC News in an interview that aired in part yesterday.

Two-thirds of Americans say they would receive the smallpox vaccine despite the risk of serious side effects, according to a new poll by the Robert Wood Johnson Foundation.

The Bush plan differs from early thinking about the best vaccination strategy for smallpox. First reports suggested that the total number of people who would be offered the inoculation—which involves scratching weakened vaccinia virus beneath the skin with a tiny fork-like device—would be 15,000.

The United States abandoned routine immunization against the virus in 1972, and the World Health Organization declared the infection eradicated in 1980. However, the United States and Russia have preserved samples of the virus, and intelligence experts fear that Iraq and North Korea have supplies of it, too.

Health officials are now stockpiling enough doses of smallpox vaccine to immunize the entire country if needed. Roughly 60 percent of the population alive today was born before routine smallpox vaccination ended, but scientists do not know how much protection they may have retained. A study of 900 people is now under way to determine just that.

So should you get the vaccine when it is available? And what if you already were immunized?

"I would not personally consider that I am protected even though I had a shot as a child," said Edward Kaplan, a Yale University smallpox vaccine expert. On the other hand, he added, people who have already been immunized are probably less likely to suffer side effects the second time around.

Pregnant women, people with HIV and AIDS, and those with certain skin conditions should not be given the smallpox vaccine in a pre-attack inoculation program. Whether they choose to do so during an outbreak depends on the scope and severity of the attack, Kaplan said.

Kaplan said he believes a voluntary system for the general public is the right approach. But making the decision to get inoculated will require careful thinking and cost-benefit analysis. "It sort of depends on what the post-attack planning is in your state," Kaplan said. "In some places I have more confidence than in others."

The Centers for Disease Control and Prevention (CDC) announced today that it has reviewed smallpox vaccination plans from 49 states and four cities. The plans, which vary by jurisdiction, outline where the shots would be administered. According to the CDC, the vaccine will be available at 3,300 healthcare facilities and hundreds of clinics nationwide.

Kaplan said some states are considering a strategy of "ring vaccination," in which a small group of first responders is tasked with trying to contain an outbreak by inoculating as few people as necessary. That approach, he said, makes him nervous.

"If I was in a state where that was the agreed-upon policy, I would think very hard about getting vaccinated on a voluntary basis," said Kaplan, who strongly prefers a much broader tack where an entire city would be offered the protection. Ironically, the more people who opt for vaccination, the more prudent waiting becomes, since those who do get the vaccine serve as a buffer for the rest.

But not every expert agrees with the Bush decision. Dr. John Neff, a pediatrician at the University of Washington who has studied smallpox, said the public does not need to be vaccinated before an outbreak.

"Right now, unless we know more about what the President is thinking, I think that the potential risk from an adverse event is higher than from getting and dying from smallpox," Neff said. "The first line of defense makes a certain amount of sense. To have everybody get it on their own choice makes no sense," said Neff, who argues that the Bush decision was driven more by the looming war in Iraq than consideration about what is scientifically appropriate.

Unnecessarily encouraging mass inoculations might have devastating repercussions in the rest of the world, said Neff. The United States can control an outbreak within its borders, but it almost certainly cannot keep the infection within them, he said. Although Europe might have enough vaccine to quash a limited smallpox outbreak if it crops up there, South American nations almost certainly do not.

"If we use [vaccine stocks] up by having unnecessary vaccinations we would not be looked upon favorably by the rest of the world and we couldn't help them," Neff said.

Always consult your physician for more information.


Online Resources

(Our Organization is not responsible for the content of Internet sites.)

Centers for Disease Control and Prevention (CDC)

National Center for Allergy and Infectious Diseases, Part of the National Institutes of Health (NIH)

World Health Organization (WHO)

For more information on infectious disease, please visit the Infectious Disease information module on this Web site.


Bush Approves Optional Smallpox Shots for All Americans

< December 12, 2002 > President Bush has approved a plan to offer the risky smallpox vaccine to all Americans, but not to make it mandatory, ABC News says.

The shots will be required only for front-line health workers and military personnel beginning sometime next year. All Americans will have the option to be vaccinated by some time in 2004, when enough of the vaccine will be available to inoculate the entire population.

Older stockpiles of the vaccine will not be used unless there is a bioterror attack before enough new vaccine is produced.

The White House plans a major public education campaign before the vaccine is made widely available. Studies from the 1960s predicted that about 15 of every one million people would suffer a serious reaction to the vaccine, and one or two of them would die.

Bush revealed details of the plan during an interview with ABC News' Barbara Walters. It will be broadcast in its entirety on Friday's 20/20. Bush will discuss details with the American people tomorrow before the broadcast, administration officials said.

Two of Three Americans Favor Smallpox Vaccine, Poll Says

< December 12, 2002 > Two out of three Americans say they would get the smallpox vaccine despite the risk of serious side effects, according to a new poll.

A telephone survey of 1,002 adults, conducted for the Robert Wood Johnson Foundation, indicates that people are more concerned about smallpox being used in a bioterror attack than they are about possible vaccine repercussions, the Orlando, Fla., TV station WESH 2 reports.

Most respondents also said that when it came to information about how to protect themselves, they had more faith in their physicians than the government. And they believe America is only slightly better prepared to deal with a bioterrorism assault than it was a year ago when anthrax was sent through the mail.

Always consult your physician for more information.


What Is Smallpox?

Smallpox is a contagious, sometimes fatal, infectious disease. There is no specific treatment for smallpox, but protection from the disease is possible with vaccination.

What Are the Different Forms of Smallpox?

There are two clinical forms of smallpox:

  • variola major - the most severe and most common form of smallpox. Variola major presents with a more extensive rash and higher fever. There are four subtypes of variola major smallpox:

    • ordinary - the most frequent type, accounting for 90 percent or more of cases

    • modified - a mild subtype of variola major; occurs in previously vaccinated persons

    • flat -  a rare and very severe subtype of variola major

    • hemorrhagic -  a rare and very severe subtype of variola major

 

Historically, variola major has an overall fatality rate of about 30 percent; however, flat and hemorrhagic smallpox usually are fatal.

  • variola minor - a less common form of the smallpox disease and a much less severe type. Death rates from variola minor are historically 1percent or less.

According to the Centers for Disease Control and Prevention (CDC), smallpox outbreaks have occurred from time to time for thousands of years, but the disease is now eradicated after a successful worldwide vaccination program. The last case of smallpox in the United States was in 1949. The last naturally occurring case in the world was in Somalia in 1977. After the disease was eliminated from the world, routine vaccination against smallpox among the general public was stopped because it was no longer necessary for prevention.

Always consult your physician for more information.















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